Lone Assassin
True Damage + Penetration + Anti-Heal + Movement Speed
Assassin/Mage
One thing about Lunox is that you should focus on maximizing your magic penetration rather the magic power itself. Assassin Emblems gives you the highest penetration that is good to for the burst continuous damage, followed by Rupture for additional pen and more importantly, When I play Lunox - I realized that Lunox is good being a sneaky assassin hiding in a bush. Lastly, Lunox is an HP-based damaged hero, that is why Impure Rage will give him the edge on this quirk.
Battle Spell
Flicker is a very good spell in her famous RUBY-DD Combo. The point here is to surprise enemy specially during team fights and ganking
Early Game
Because Lunox can easily clear minion waves means she can easily rotate. Maximize first the passive of Sky Piercer. This is the part where she became an Assassin-Finisher. You should participate late in the early game team fights, then finish what unsuccessful attack that your team posed to the enemy hero.
Mid Game
You probably have the holy crystal. Which is base on my experience, a less 5000hp hero can be easily killed by her combo. Ultimate (Dark) - Second Skill + at least 5 darkening of the 1st Skill. Just make sure you don't get stunned. And it is only good when ganking solo enemy hero.
Late Game
Just some throw RUBY DD Combo.
Best With Atlas
100% co-op win rate
Altas great CC are perfect in the Ruby DD Combo.
Watch Out For Kagura
100% counter win rate
Lunox need to near enemy heroes and Kagura has a quirk to escape her combo.